cobas z 480


Real-time polymerase chain reaction (PCR) technology system for the detection of mutations in the KRAS, BRAF and EGFR genes of tumor samples

The cobas® 4800 System for oncology is a real-time PCR system for the detection of mutations in the KRAS, BRAF and EGFR genes of tumor samples. It features manual sample preparation, PCR technology for amplification and detection combined with automated results interpretation and reporting.


Features and Benefits


  • Streamlined manual DNA sample preparation
  • The intuitive graphical user interface provides all instructions to operate the system
  • The unique design provides temperature uniformity to ensure accurate amplification with every sample
  • Automated results interpretation
  • Automated, standardized result reports


  • Workflow simplicity
  • Results integrity is achieved by using the proprietary AmpErase enzymes for contamination control which help prevent carryover and detection of previously amplified products
  • Reproducibility is ensured by the unique Therma-Base layer which provides uniform heating and cooling across the entire plate
  • Lab efficiency is improved by automated result interpretation and reporting